The Center for Structural Biology (CSB), housed in the Life Sciences Institute, is a comprehensive structural biology resource for researchers at the University of Michigan and surrounding areas.

The U-M Life Sciences Institute is home to a world-class cryo-EM laboratory, with state-of-the-art instruments and faculty specializing in this emerging field.

The Center for Chemical Genomics provides high-throughput screening of extensive small molecule, natural product and siRNA libraries – along with assay development and optimization – for basic biology and drug discovery projects.

Our mass spectrometry facility provides both open and assisted services for the analysis of proteins and small molecules, as well as training on use of the instruments.

State of the art NMR instruments provide the ability to obtain structural, dynamic and kinetic information on biological macromolecules including protein, RNA and DNA. Automated sampling devices also make it ideal for metabolomics and high throughput data collection.

CMI/PICA is a shared resource aimed at providing state-of-the-art imaging services for the research community. The CMI is a central, diverse, and dynamic combination of facilities wherein exchange of techniques and ideas can occur, fostering productive interdisciplinary collaborations in research.

The CyTOF Core at the University of Michigan was founded in 2018 to promote a collaborative and interdisciplinary environment on the University of Michigan’s North Campus. Our goal is to share our equipment and expertise with ambitious researchers to help solve the most challenging problems in cellu

The Rogel Cancer Center Immunology Core provides research assistance to members of the university, with priority given to Rogel Cancer Center members.

Enhancing existing research by centralizing histologic efforts to achieve high quality and reasonably priced histology for center investigators, and to ensure, in collaboration with the other Cores, a cost-effective, efficient, integrated, hierarchical approach to evaluation of tissue phenotypes.

The goal of the PRF is to assist researchers in designing proteomic experiments, maintain state-of-the-art instrumentation, provide technical expertise and bioinformatics support during both discovery and validation phases of proteomic experiments.

The Central Biorepository, a unit of the University of Michigan Medical School Office of Research, facilitates discovery and improves healthcare outcomes by providing high-quality, highly annotated human biospecimens donated for basic, clinical and translational research.

The BRCF Bioinformatics Core provides bioinformatics analysis to support research activities.

The BRCF Biomedical Research Store provides on-site procurement of enzymes, reagents, and kits used in molecular, cell biology, and some protein chemistry.

The BRCF Epigenomics Core provides sample quality control, library preparation, and sequencing for the study of cytosine and histone modifications.

The BRCF Flow Cytometry Core provides instrumentation and expertise for flow cytometric analysis or cell sorting.

The BRCF Metabolomics Core provides determination of small quantity metabolites in cells, tissues, and biological fluids.

The BRCF Microscopy Core provides instrumentation and expertise for microscopic imaging studies of cell and tissue morphology and ultrastructure.

The Proteomics & Peptide Synthesis Core offers research services in qualitative and quantitative proteomics including Pathway Analysis. We are a full-service core and provide expert services from project consultation all the way to data analysis, interpretation and software training.

The BRCF Transgenic Animal Model Core provides expertise in CRISPR/Cas9 in transgenic mice, rats, and embryonic stem cell technology.

The Vector Core produces gene transfer vectors that facilitate the transfer of specific genes into either normal or aberrant cells. We also provide full service gene editing in cell lines using CRISPR technology.

The Biochemical Nuclear Magnetic Resonance (BNMR) Laboratory provides research support for graduate students, postdocs, and faculty. We offer quantitative metabolomics NMR services for different biological fluids including whole blood, serum, plasma, urine, cell media.