Welcome!
The Biological Mass Spectrometry facility provides specialized MS services to the University of Michigan research community. The major areas of focus of the lab are:
Analysis of intact proteins, multi-protein complexes, and protein structure.
Identification and purification of compounds from complex mixtures coupled with quantitative analysis.
Purification using mass directed autopurification liquid chromatography.
Users can be trained on the instruments for walk-up use or samples can be submitted for analysis.
For trained users, use shedule equipment tab to select instrument, day, time and usage type.
All other users, use request services tab to start a service or project request.
| Carmen Dunbar, PhD | Managing Director | 734-647-2878 | carmdun@umich.edu |
| Hours | Location |
|
Staffed Mon - Fri 8:00 AM - 5:00 PM |
Room A525 |
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Carmen Dunbar, PhD |
Managing Director
|
734-647-2878
|
carmdun@umich.edu
|
A856
|
| Tracy Stevenson |
Facilities Manager
|
734-764-7316
|
steventi@umich.edu
|
1500C
|
| Brandon Ruotolo, PhD |
Faculty Director
|
734-615-9852
|
bruotolo@umich.edu
|
4549
|
| Service list |
| ► Intact Mass (1) | |||
| Name | Description | Price | |
|---|---|---|---|
| Small Molecule Infusion |
Direct infusion using standard ESI on TSQ-Quantis. |
Internal
$29.00
/hr
External $87.00 Sample |
|
| ► LC-MS (3) | |||
| Name | Description | Price | |
| LC-MS/MS |
LC separation followed by MS analysis on TSQ-Quantis |
Internal
$23.00
/hr
External $69.00 /hr |
|
| Preparative LC-MS |
LC purification and fraction collection using mass directed Waters autopurification system. |
Internal
$39.00
/hr
External $117.00 /hr |
|
| Method Development |
For those looking to develope any LC based method. |
Internal
$33.00
/hr
External $99.00 /hr |
|
| ► Native Mass Spec (3) | |||
| Name | Description | Price | |
| Native Nano-ESI MS |
Using QE UHMR analysis in native conditions using nano ESI. |
Internal
$47.00
Sample
External $141.00 Sample |
|
| Native MS |
Using QE UHMR analysis under native conditions using standard ESI. |
Internal
$44.00
Sample
External $132.00 Sample |
|
| Charge Detection Mass Spectrometry (CDMS) |
Using Q-Exactive UHMR charge detection mass spectrometry for intact mass analysis of molecules >200kDa. |
Internal
$47.00
Sample
External $141.00 Sample |
|
| ► Ion Mobility (4) | |||
| Name | Description | Price | |
| Nano-ESI IM-MS (infusion) |
Cyclic IM-MS direct infusion using nano ESI |
Internal
$37.00
/hr
External $111.00 /hr |
|
| Nano-ESI LC-IM-MS |
LC separation coupled with Cyclic IM-MS using nano ESI |
Internal
$31.00
/hr
External $93.00 /hr |
|
| IM-MS (infusion) |
Cyclic IM-MS direct infusion using standard ESI |
Internal
$35.00
/hr
External $105.00 /hr |
|
| LC IM-MS |
LC separation coupled with Cyclic IM-MS. |
Internal
$29.00
/hr
External $87.00 /hr |
|
