UMICH Advanced Genomics Core

An Introduction to the Advanced Genomics Core

The Advanced Genomics Core is a state-of-the-art facility dedicated to providing cutting-edge genomic services and support to researchers. Equipped with the latest technology and staffed by highly skilled experts, the Advanced Genomics Core enables scientists to unravel the complexities of the genome and advance discoveries across various fields of study.

Leadership

Olivia I. Koues, Ph.D. - Director

Thomas E. Wilson, M.D. Ph.D. - Faculty Director

Location and hours of operation

Business Hours

Location

Monday-Friday:

8:00 am - 5:00 pm

Saturday and Sunday: Closed

North Campus Research Complex (NCRC)

Building 14 • Room 122

2800 Plymouth Road

Ann Arbor, MI 48109-2800

Links and Resources

Our Website - https://brcf.medicine.umich.edu/cores/advanced-genomics/

Contacts

Name	Role	Phone	Email	Location
Olivia Koues, Ph.D.	Core Director	(734) 764-8531	advanced-genomics@umich.edu	NCRC14-119

Services Offered (Price List)

Name	Description	Price
10x ATAC		Internal $1,948.00 each External $2,727.20 each
10x CytAssist 11 x 11		Internal $7,551.00 each External $10,571.40 each
10x CytAssist 6.5 x 6.5		Internal $3,995.00 each External $5,593.00 each
10x CytAssist HD		Internal $6,038.00 each External $8,453.20 each
10x GEX (3' or 5')		Internal $1,982.00 each External $2,774.80 each
10x GEX (3' or 5') OCM		Internal $2,864.00 each External $4,009.60 each
10x Immune Profiling Add-on		Internal $217.00 each External $303.80 each
10x Multiome		Internal $3,183.00 each External $4,456.20 each
10x scRNA Flex		Internal $6,479.00 each External $9,070.60 each
10x Visium (FF)		Internal $6,684.00 each External $9,357.60 each
10x Visium Feature Add-on		Internal $1,477.00 each External $2,067.80 each
10x Visium GEX (w/o slide)		Internal $1,977.00 each External $2,767.80 each
10x Xenium (custom probes)		Internal $2,344.00 each External $3,281.60 each
10x Xenium (no reagents)		Internal $925.00 each External $1,295.00 each
10x Xenium 5K		Internal $8,313.00 each External $11,638.20 each
10x Xenium Segmentation Add-on		Internal $806.00 each External $1,128.40 each
10x Xenium Tissue Specific		Internal $2,294.00 each External $3,211.60 each
Archived Data Reprocessing		Internal $175.00 each External $245.00 each
Aviti Sequencing w/o flow cell		Internal $418.00 each External $585.20 each
Aviti24 Cytoprofiling w/o panel		Internal $1,114.00 each External $1,559.60 each
Aviti24 High Output 150 Cycle		Internal $1,741.00 each External $2,437.40 each
Aviti24 High Output 300 Cycle		Internal $2,392.00 each External $3,348.80 each
Aviti24 High Output 600 Cycle		Internal $2,707.00 each External $3,789.80 each
Aviti24 Low Output 150 Cycle		Internal $1,078.00 each External $1,509.20 each
Aviti24 Low Output 300 Cycle		Internal $1,295.00 each External $1,813.00 each
Aviti24 Mid Output 150 Cycle		Internal $1,372.00 each External $1,920.80 each
Aviti24 Mid Output 300 Cycle		Internal $1,588.00 each External $2,223.20 each
Aviti24 Mid Output 600 Cycle		Internal $1,872.00 each External $2,620.80 each
Bead Clean-up		Internal $29.00 each External $40.60 each
Bead Clean-up (plate rate)		Internal $329.00 each External $460.60 each
Bruker Spatial (w/o reagents)		Internal $2,438.00 each External $3,413.20 each
Cell/Nuclei/Tissue Fixation		Internal $73.00 each External $102.20 each
CurioAssay (w/o Tiles)		Internal $971.00 each External $1,359.40 each
Custom Capture (client kit)		Internal $231.00 each External $323.40 each
DNA Library		Internal $96.00 each External $134.40 each
DNA Pooled Library (96 samples)		Internal $3,201.00 each External $4,481.40 each
DNA/RNA QC		Internal $19.00 each External $26.60 each
Feature Library Add-on		Internal $172.00 each External $240.80 each
G4 Library Conversion		Internal $67.00 each External $93.80 each
G4 Sequencing (w/o flow cell)		Internal $199.00 each External $278.60 each
Generalized Tech Time		Internal $59.00 each External $82.60 each
Illumina Bead Array (w/o chips)		Internal $2,205.00 each External $2,205.00 each
Library Prep (client kit)		Internal $50.00 each External $70.00 each
Long Read Covaris Shearing		Internal $115.00 each External $161.00 each
Long Read Enrichment Add-on		Internal $102.00 each External $142.80 each
Long Read Size Selection		Internal $215.00 each External $301.00 each
MiSeq Sequencing w/o flow cell		Internal $451.00 each External $631.40 each
Next Sequencing w/o flow cell		Internal $1,743.00 each External $2,440.20 each
NGS Library QC		Internal $51.00 each External $71.40 each
Nova6000 Sequencing w/o flow cell		Internal $4,407.00 each External $6,169.80 each
NovaX 1.5B 100 cycle		Internal $3,247.00 each External $4,545.80 each
NovaX 1.5B 200 cycle		Internal $3,812.00 each External $5,336.80 each
NovaX 10B 100 cycle		Internal $12,081.00 each External $16,913.40 each
NovaX 10B 200 cycle		Internal $14,224.00 each External $19,913.60 each
NovaX 10B 300 cycle		Internal $14,976.00 each External $20,966.40 each
NovaX 25B 100 cycle		Internal $20,369.00 each External $28,516.60 each
NovaX 25B 200 cycle		Internal $23,434.00 each External $32,807.60 each
NovaX 25B 300 cycle		Internal $25,601.00 each External $35,841.40 each
NovaX Sequencing w/o flow cell		Internal $4,276.00 each External $5,986.40 each
Nuclease Flush/Extra Lib Add-on		Internal $269.00 each External $376.60 each
Nuclei Isolation		Internal $153.00 each External $214.20 each
Olink Explore HT		Internal $79.00 each External $110.60 each
ONT Amplicon Sequencing		Internal $40.00 each External $56.00 each
ONT DNA Prep		Internal $496.00 each External $694.40 each
ONT Load & Go		Internal $578.00 each External $809.20 each
ONT Multiplexing Prep Add-on		Internal $135.00 each External $189.00 each
ONT RNA Prep		Internal $767.00 each External $1,073.80 each
ONT Sample QC		Internal $56.00 each External $78.40 each
PacBio Multiplex Prep Add-on		Internal $103.00 each External $144.20 each
PacBio Prep		Internal $501.00 each External $701.40 each
PacBio SMRT Cell Sequencing		Internal $1,660.00 each External $2,324.00 each
Prep plate-based (client kit)		Internal $1,478.00 each External $2,069.20 each
PromethION Sequencing (w/o flow cell)		Internal $834.00 each External $1,167.60 each
qPCR Instrument Usage		Internal $118.00 each External $165.20 each
Quant & Normalization		Internal $8.00 each External $11.20 each
RNA (polyA-enrichment) Library		Internal $168.00 each External $235.20 each
RNA (ribo-depletion) Library		Internal $232.00 each External $324.80 each
Seq-Scope Chip		Internal $1,246.00 each External $1,744.40 each
Seq-Scope Slide Processing		Internal $1,865.00 each External $2,611.00 each
Single Cell Prep (w/o sc kit)		Internal $803.00 each External $1,124.20 each
Small RNA Library		Internal $223.00 each External $312.20 each
Spatial H&E only		Internal $30.00 each External $42.00 each
Spatial RNA Assessment		Internal $47.00 each External $65.80 each
SPLiT-seq (client kit)		Internal $2,074.00 each External $2,903.60 each
Tapestri (client kit)		Internal $691.00 each External $967.40 each
Tissue Block Processing		Internal $163.00 each External $228.20 each
Tissue Dissociation		Internal $43.00 each External $60.20 each
Trinity WES, 20x		Internal $226.00 Sample External $316.40 Sample
TruSight Oncology DNA only		Internal $646.00 each External $904.40 each
Whole Exome Capture		Internal $660.00 each External $924.00 each
Xenium Single Slide Run Add-on		Internal $2,463.00 each External $3,448.20 each

Search available services: View: by category alphabetically

Name	Description	Price
▼ ► Illumina Library Prep (11)
Olink Explore HT		Internal $79.00 each External $110.60 each
DNA Pooled Library (96 samples)		Internal $3,201.00 each External $4,481.40 each
DNA Library		Internal $96.00 each External $134.40 each
RNA (polyA-enrichment) Library		Internal $168.00 each External $235.20 each
RNA (ribo-depletion) Library		Internal $232.00 each External $324.80 each
Small RNA Library		Internal $223.00 each External $312.20 each
Whole Exome Capture		Internal $660.00 each External $924.00 each
TruSight Oncology DNA only		Internal $646.00 each External $904.40 each
Custom Capture (client kit)		Internal $231.00 each External $323.40 each
Library Prep (client kit)		Internal $50.00 each External $70.00 each
Prep plate-based (client kit)		Internal $1,478.00 each External $2,069.20 each
▼ ► Illumina Sequencing (12)
Name	Description	Price
NovaX 1.5B 100 cycle		Internal $3,247.00 each External $4,545.80 each
NovaX 1.5B 200 cycle		Internal $3,812.00 each External $5,336.80 each
NovaX 10B 100 cycle		Internal $12,081.00 each External $16,913.40 each
NovaX 10B 200 cycle		Internal $14,224.00 each External $19,913.60 each
NovaX 10B 300 cycle		Internal $14,976.00 each External $20,966.40 each
NovaX 25B 100 cycle		Internal $20,369.00 each External $28,516.60 each
NovaX 25B 200 cycle		Internal $23,434.00 each External $32,807.60 each
NovaX 25B 300 cycle		Internal $25,601.00 each External $35,841.40 each
NovaX Sequencing w/o flow cell		Internal $4,276.00 each External $5,986.40 each
Nova6000 Sequencing w/o flow cell		Internal $4,407.00 each External $6,169.80 each
MiSeq Sequencing w/o flow cell		Internal $451.00 each External $631.40 each
Next Sequencing w/o flow cell		Internal $1,743.00 each External $2,440.20 each
▼ ► Oxford Nanopore (8)
Name	Description	Price
ONT Amplicon Sequencing		Internal $40.00 each External $56.00 each
ONT DNA Prep		Internal $496.00 each External $694.40 each
ONT Multiplexing Prep Add-on		Internal $135.00 each External $189.00 each
ONT RNA Prep		Internal $767.00 each External $1,073.80 each
ONT Sample QC		Internal $56.00 each External $78.40 each
PromethION Sequencing (w/o flow cell)		Internal $834.00 each External $1,167.60 each
Nuclease Flush/Extra Lib Add-on		Internal $269.00 each External $376.60 each
ONT Load & Go		Internal $578.00 each External $809.20 each
▼ ► Single Cell (13)
Name	Description	Price
Cell/Nuclei/Tissue Fixation		Internal $73.00 each External $102.20 each
Nuclei Isolation		Internal $153.00 each External $214.20 each
SPLiT-seq (client kit)		Internal $2,074.00 each External $2,903.60 each
10x scRNA Flex		Internal $6,479.00 each External $9,070.60 each
10x GEX (3' or 5')		Internal $1,982.00 each External $2,774.80 each
10x GEX (3' or 5') OCM		Internal $2,864.00 each External $4,009.60 each
10x Immune Profiling Add-on		Internal $217.00 each External $303.80 each
10x ATAC		Internal $1,948.00 each External $2,727.20 each
10x Multiome		Internal $3,183.00 each External $4,456.20 each
Feature Library Add-on		Internal $172.00 each External $240.80 each
Single Cell Prep (w/o sc kit)		Internal $803.00 each External $1,124.20 each
Tapestri (client kit)		Internal $691.00 each External $967.40 each
Tissue Dissociation		Internal $43.00 each External $60.20 each
▼ ► Spatialomics (20)
Name	Description	Price
10x CytAssist HD		Internal $6,038.00 each External $8,453.20 each
10x CytAssist 6.5 x 6.5		Internal $3,995.00 each External $5,593.00 each
10x CytAssist 11 x 11		Internal $7,551.00 each External $10,571.40 each
10x Xenium (custom probes)		Internal $2,344.00 each External $3,281.60 each
10x Xenium (no reagents)		Internal $925.00 each External $1,295.00 each
10x Xenium 5K		Internal $8,313.00 each External $11,638.20 each
10x Xenium Segmentation Add-on		Internal $806.00 each External $1,128.40 each
10x Xenium Tissue Specific		Internal $2,294.00 each External $3,211.60 each
Aviti24 Cytoprofiling w/o panel		Internal $1,114.00 each External $1,559.60 each
CurioAssay (w/o Tiles)		Internal $971.00 each External $1,359.40 each
Seq-Scope Chip		Internal $1,246.00 each External $1,744.40 each
Seq-Scope Slide Processing		Internal $1,865.00 each External $2,611.00 each
Spatial RNA Assessment		Internal $47.00 each External $65.80 each
Xenium Single Slide Run Add-on		Internal $2,463.00 each External $3,448.20 each
10x Visium Feature Add-on		Internal $1,477.00 each External $2,067.80 each
10x Visium (FF)		Internal $6,684.00 each External $9,357.60 each
10x Visium GEX (w/o slide)		Internal $1,977.00 each External $2,767.80 each
Bruker Spatial (w/o reagents)		Internal $2,438.00 each External $3,413.20 each
Tissue Block Processing		Internal $163.00 each External $228.20 each
Spatial H&E only		Internal $30.00 each External $42.00 each
▼ ► Other Services (14)
Name	Description	Price
Bead Clean-up (plate rate)		Internal $329.00 each External $460.60 each
G4 Library Conversion		Internal $67.00 each External $93.80 each
G4 Sequencing (w/o flow cell)		Internal $199.00 each External $278.60 each
Long Read Covaris Shearing		Internal $115.00 each External $161.00 each
Long Read Enrichment Add-on		Internal $102.00 each External $142.80 each
Long Read Size Selection		Internal $215.00 each External $301.00 each
DNA/RNA QC		Internal $19.00 each External $26.60 each
NGS Library QC		Internal $51.00 each External $71.40 each
Bead Clean-up		Internal $29.00 each External $40.60 each
Quant & Normalization		Internal $8.00 each External $11.20 each
Illumina Bead Array (w/o chips)		Internal $2,205.00 each External $2,205.00 each
qPCR Instrument Usage		Internal $118.00 each External $165.20 each
Archived Data Reprocessing		Internal $175.00 each External $245.00 each
Generalized Tech Time		Internal $59.00 each External $82.60 each
▼ ► Pacific Biosciences Sequencing (3)
Name	Description	Price
PacBio Multiplex Prep Add-on		Internal $103.00 each External $144.20 each
PacBio Prep		Internal $501.00 each External $701.40 each
PacBio SMRT Cell Sequencing		Internal $1,660.00 each External $2,324.00 each
▼ ► Element Sequencing (10)
Name	Description	Price
Aviti24 Low Output 150 Cycle		Internal $1,078.00 each External $1,509.20 each
Aviti24 Low Output 300 Cycle		Internal $1,295.00 each External $1,813.00 each
Aviti24 Mid Output 150 Cycle		Internal $1,372.00 each External $1,920.80 each
Aviti24 Mid Output 300 Cycle		Internal $1,588.00 each External $2,223.20 each
Aviti24 Mid Output 600 Cycle		Internal $1,872.00 each External $2,620.80 each
Aviti24 High Output 150 Cycle		Internal $1,741.00 each External $2,437.40 each
Aviti24 High Output 300 Cycle		Internal $2,392.00 each External $3,348.80 each
Aviti24 High Output 600 Cycle		Internal $2,707.00 each External $3,789.80 each
Trinity WES, 20x		Internal $226.00 Sample External $316.40 Sample
Aviti Sequencing w/o flow cell		Internal $418.00 each External $585.20 each