UMICH Advanced Genomics Core

An Introduction to the Advanced Genomics Core

The University of Michigan Advanced Genomics Core (formerly the DNA Sequencing Core), part of the Biomedical Research Core Facilities within the Office of Research, provides high-quality, low-cost advanced genomic analysis for research clients on a recharge basis. The Core occupies approximately 10,000 square feet of laboratory space in the North Campus Research Complex, with 30 highly trained individuals on staff to help you. We operate a wide variety of instruments that perform genotyping, gene expression analysis, nucleic acid quantification and quality control, next-generation sequencing and single cell analyses.

The Advanced Genomics Core is continuously changing to adapt to the latest technologies. We are a full-service Core, and work closely with our investigators to meet their needs and make their research as successful as possible.

Leadership

Olivia I. Koues, Ph.D. - Managing Director

Thomas E. Wilson, M.D. Ph.D. - Faculty Director

Location and hours of operation

Business Hours

Location

Monday-Friday:

8:30 am - 12:15 pm
1:15 pm - 4:30 pm

Saturday and Sunday: Closed

North Campus Research Complex (NCRC)

Building 14 • Room 122

2800 Plymouth Road

Ann Arbor, MI 48109-2800

See all sample drop-off locations here

Links and Resources

Our Website - https://brcf.medicine.umich.edu/cores/advanced-genomics/

Contacts

Name	Role	Phone	Email	Location
Olivia Koues, Ph.D.	Managing Director	(734) 764-8531	okoues@med.umich.edu	NCRC14-119

Services Offered (Price List)

Name	Description	Price
10X HMW DNA Library, per sample		Internal $349.00 each External $488.60 each
10X SC Immune Profiling , per sample		Internal $1,956.00 each External $2,738.40 each
10X Single Cell ATAC, per sample		Internal $1,803.00 each External $2,524.20 each
10X Single Cell CNV, per sample		Internal $1,948.00 each External $2,727.20 each
10X Single Cell Expression, per sample		Internal $1,867.00 each External $2,613.80 each
10X Target Enrichment, per sample		Internal $200.00 each External $280.00 each
3'-mRNA Library (QuantSeq), per sample		Internal $61.00 each External $85.40 each
Aliquot/Transfer DNA, per sample		Internal $1.10 each External $1.54 each
Custom Capture - client kit, per capture		Internal $219.00 each External $306.60 each
DNA Extraction, Saliva, per sample		Internal $17.30 each External $24.22 each
DNA Extraction, per sample		Internal $25.50 each External $35.70 each
DNA Library (>32 samples), per sample		Internal $37.00 each External $51.80 each
DNA Library - client kit, per sample		Internal $81.00 each External $113.40 each
DNA Library, per sample		Internal $125.00 each External $175.00 each
DNA QC, per sample		Internal $10.00 each External $14.00 each
FragAnalysis, CE Loading Plate, per plate		Internal $43.00 each External $60.20 each
FragAnalysis, IdentifilerPlus, per sample		Internal $44.00 each External $61.60 each
FragAnalysis, Instrument Usage, per run		Internal $67.00 each External $93.80 each
IDT Exome Capture, per capture		Internal $568.00 each External $795.20 each
Illumina Bead Array (w/o chip), per plate		Internal $851.00 each External $1,191.40 each
Library QC, per sample		Internal $22.00 each External $30.80 each
Low Input DNA Library, per sample		Internal $123.00 each External $172.20 each
Low Input RNA/Direct Lysis Lib, per sample		Internal $111.00 each External $155.40 each
MiSeq (Micro) 300 cycle, per flow cell		Internal $766.00 each External $1,072.40 each
MiSeq (Nano) 300 cycle, per flow cell		Internal $624.00 each External $873.60 each
MiSeq (Nano) 500 cycle, per flow cell		Internal $713.00 each External $998.20 each
MiSeq (V2) 300 cycle, per flow cell		Internal $1,355.00 each External $1,897.00 each
MiSeq (V2) 50 cycle, per flow cell		Internal $1,131.00 each External $1,583.40 each
MiSeq (V2) 500 cycle, per flow cell		Internal $1,601.00 each External $2,241.40 each
MiSeq (V3) 150 cycle, per flow cell		Internal $1,214.00 each External $1,699.60 each
MiSeq (V3) 600 cycle, per flow cell		Internal $1,825.00 each External $2,555.00 each
MiSeq/NextSeq Clust Only, per flow cell		Internal $466.00 each External $650.40 each
NextSeq (HO) 150 cycle, per flow cell		Internal $3,214.00 each External $4,499.60 each
NextSeq (HO) 300 cycle, per flow cell		Internal $4,867.00 each External $6,813.80 each
NextSeq (HO) 75 cycle, per flow cell		Internal $1,899.00 each External $2,658.60 each
NextSeq (MO) 150 cycle, per flow cell		Internal $1,511.00 each External $2,155.40 each
NextSeq (MO) 300 cycle, per flow cell		Internal $2,150.00 each External $3,010.00 each
NovaSeq (S1) 100 cycle, per flow cell		Internal $6,624.00 each External $9,273.60 each
NovaSeq (S1) 200 cycle, per flow cell		Internal $8,183.00 each External $11,456.20 each
NovaSeq (S1) 300 cycle, per flow cell		Internal $9,408.00 each External $13,171.20 each
NovaSeq (S2) 100 cycle, per flow cell		Internal $12,792.00 each External $17,908.80 each
NovaSeq (S2) 200 cycle, per flow cell		Internal $15,543.00 each External $21,760.20 each
NovaSeq (S2) 300 cycle, per flow cell		Internal $19,195.00 each External $26,873.00 each
NovaSeq (S4) 200 cycle, per flow cell		Internal $27,848.00 each External $38,987.20 each
NovaSeq (S4) 300 cycle, per flow cell		Internal $31,709.00 each External $44,392.60 each
NovaSeq (SP) 100 cycle, per flow cell		Internal $4,179.00 each External $6,606.60 each
NovaSeq (SP) 300 cycle, per flow cell		Internal $6,501.00 each External $9,101.40 each
NovaSeq (SP) 500 cycle, per flow cell		Internal $8,372.00 each External $11,720.80 each
NovaSeq Clustering Only, per flow cell		Internal $2,053.00 each External $2,874.20 each
OpenArray mRNA Panels, per sample		Internal $215.00 each External $301.00 each
OpenArray miRNA Panels, per sample		Internal $254.00 each External $355.60 each
PCR-free DNA Library, per sample		Internal $120.00 each External $168.00 each
PyroMark Full Plate, per run		Internal $125.00 each External $175.00 each
RNA Library, client kit, per sample		Internal $90.00 each External $126.00 each
RNA QC, per sample		Internal $14.00 each External $19.60 each
RT2 Profiler Arrays, per sample		Internal $308.00 each External $431.20 each
Stranded mRNA Library, per sample		Internal $133.00 each External $186.20 each
Targeted Seq - client kit, per plate		Internal $459.00 each External $642.60 each
Total RNA Library, per sample		Inquire
qPCR Instrument Usage, per run		Internal $22.00 each External $30.80 each
small RNA Library, per sample		Internal $194.00 each External $271.60 each

Search available services: View: by category alphabetically

Name	Description	Price
▼ ► Quality Control Services (3)
DNA QC, per sample		Internal $10.00 each External $14.00 each
Library QC, per sample		Internal $22.00 each External $30.80 each
RNA QC, per sample		Internal $14.00 each External $19.60 each
▼ ► NGS Library Prep Services (14)
Name	Description	Price
Stranded mRNA Library, per sample		Internal $133.00 each External $186.20 each
Total RNA Library, per sample		Inquire
3'-mRNA Library (QuantSeq), per sample		Internal $61.00 each External $85.40 each
RNA Library, client kit, per sample		Internal $90.00 each External $126.00 each
small RNA Library, per sample		Internal $194.00 each External $271.60 each
DNA Library, per sample		Internal $125.00 each External $175.00 each
DNA Library (>32 samples), per sample		Internal $37.00 each External $51.80 each
PCR-free DNA Library, per sample		Internal $120.00 each External $168.00 each
10X HMW DNA Library, per sample		Internal $349.00 each External $488.60 each
Low Input DNA Library, per sample		Internal $123.00 each External $172.20 each
DNA Library - client kit, per sample		Internal $81.00 each External $113.40 each
Custom Capture - client kit, per capture		Internal $219.00 each External $306.60 each
IDT Exome Capture, per capture		Internal $568.00 each External $795.20 each
Targeted Seq - client kit, per plate		Internal $459.00 each External $642.60 each
▼ ► Single Cell Services (6)
Name	Description	Price
10X SC Immune Profiling , per sample		Internal $1,956.00 each External $2,738.40 each
10X Single Cell ATAC, per sample		Internal $1,803.00 each External $2,524.20 each
10X Single Cell CNV, per sample		Internal $1,948.00 each External $2,727.20 each
10X Single Cell Expression, per sample		Internal $1,867.00 each External $2,613.80 each
10X Target Enrichment, per sample		Internal $200.00 each External $280.00 each
Low Input RNA/Direct Lysis Lib, per sample		Internal $111.00 each External $155.40 each
▼ ► Next Generation Sequencing Services (26)
Name	Description	Price
MiSeq (Micro) 300 cycle, per flow cell		Internal $766.00 each External $1,072.40 each
MiSeq (Nano) 300 cycle, per flow cell		Internal $624.00 each External $873.60 each
MiSeq (Nano) 500 cycle, per flow cell		Internal $713.00 each External $998.20 each
MiSeq (V2) 300 cycle, per flow cell		Internal $1,355.00 each External $1,897.00 each
MiSeq (V2) 50 cycle, per flow cell		Internal $1,131.00 each External $1,583.40 each
MiSeq (V2) 500 cycle, per flow cell		Internal $1,601.00 each External $2,241.40 each
MiSeq (V3) 150 cycle, per flow cell		Internal $1,214.00 each External $1,699.60 each
MiSeq (V3) 600 cycle, per flow cell		Internal $1,825.00 each External $2,555.00 each
MiSeq/NextSeq Clust Only, per flow cell		Internal $466.00 each External $650.40 each
NextSeq (HO) 150 cycle, per flow cell		Internal $3,214.00 each External $4,499.60 each
NextSeq (HO) 300 cycle, per flow cell		Internal $4,867.00 each External $6,813.80 each
NextSeq (HO) 75 cycle, per flow cell		Internal $1,899.00 each External $2,658.60 each
NextSeq (MO) 150 cycle, per flow cell		Internal $1,511.00 each External $2,155.40 each
NextSeq (MO) 300 cycle, per flow cell		Internal $2,150.00 each External $3,010.00 each
NovaSeq (S1) 100 cycle, per flow cell		Internal $6,624.00 each External $9,273.60 each
NovaSeq (S1) 200 cycle, per flow cell		Internal $8,183.00 each External $11,456.20 each
NovaSeq (S1) 300 cycle, per flow cell		Internal $9,408.00 each External $13,171.20 each
NovaSeq (S2) 100 cycle, per flow cell		Internal $12,792.00 each External $17,908.80 each
NovaSeq (S2) 200 cycle, per flow cell		Internal $15,543.00 each External $21,760.20 each
NovaSeq (S2) 300 cycle, per flow cell		Internal $19,195.00 each External $26,873.00 each
NovaSeq (S4) 200 cycle, per flow cell		Internal $27,848.00 each External $38,987.20 each
NovaSeq (S4) 300 cycle, per flow cell		Internal $31,709.00 each External $44,392.60 each
NovaSeq (SP) 100 cycle, per flow cell		Internal $4,179.00 each External $6,606.60 each
NovaSeq (SP) 300 cycle, per flow cell		Internal $6,501.00 each External $9,101.40 each
NovaSeq (SP) 500 cycle, per flow cell		Internal $8,372.00 each External $11,720.80 each
NovaSeq Clustering Only, per flow cell		Internal $2,053.00 each External $2,874.20 each
▼ ► Array Services (4)
Name	Description	Price
Illumina Bead Array (w/o chip), per plate		Internal $851.00 each External $1,191.40 each
OpenArray miRNA Panels, per sample		Internal $254.00 each External $355.60 each
OpenArray mRNA Panels, per sample		Internal $215.00 each External $301.00 each
RT2 Profiler Arrays, per sample		Internal $308.00 each External $431.20 each
▼ ► Other Services (8)
Name	Description	Price
Aliquot/Transfer DNA, per sample		Internal $1.10 each External $1.54 each
DNA Extraction, per sample		Internal $25.50 each External $35.70 each
DNA Extraction, Saliva, per sample		Internal $17.30 each External $24.22 each
FragAnalysis, CE Loading Plate, per plate		Internal $43.00 each External $60.20 each
FragAnalysis, IdentifilerPlus, per sample		Internal $44.00 each External $61.60 each
FragAnalysis, Instrument Usage, per run		Internal $67.00 each External $93.80 each
PyroMark Full Plate, per run		Internal $125.00 each External $175.00 each
qPCR Instrument Usage, per run		Internal $22.00 each External $30.80 each