UMICH Advanced Genomics Core

An Introduction to the Advanced Genomics Core

The University of Michigan Advanced Genomics Core (formerly the DNA Sequencing Core), part of the Biomedical Research Core Facilities within the Office of Research, provides high-quality, low-cost advanced genomic analysis for research clients on a recharge basis. The Core occupies approximately 10,000 square feet of laboratory space in the North Campus Research Complex, with 30 highly trained individuals on staff to help you. We operate a wide variety of instruments that perform genotyping, gene expression analysis, nucleic acid quantification and quality control, next-generation sequencing and single cell analyses.

The Advanced Genomics Core is continuously changing to adapt to the latest technologies. We are a full-service Core, and work closely with our investigators to meet their needs and make their research as successful as possible.

Leadership

Olivia I. Koues, Ph.D. - Managing Director

Thomas E. Wilson, M.D. Ph.D. - Faculty Director

Location and hours of operation

Business Hours

Location

Monday-Friday:

8:30 am - 12:15 pm
1:15 pm - 4:30 pm

Saturday and Sunday: Closed

North Campus Research Complex (NCRC)

Building 14 • Room 122

2800 Plymouth Road

Ann Arbor, MI 48109-2800

Links and Resources

Our Website - https://brcf.medicine.umich.edu/cores/advanced-genomics/

Contacts

Name	Role	Phone	Email	Location
Olivia Koues, Ph.D.	Managing Director	(734) 764-8531	okoues@med.umich.edu	NCRC14-119

Services Offered (Price List)

Name	Description	Price
10X Data Processing - client prepped		Internal $127.00 each External $171.45 each
10X SC Immune Profiling		Internal $2,120.00 Sample External $2,862.00 Sample
10X Single Cell ATAC		Internal $1,732.00 Sample External $2,338.20 Sample
10X Single Cell CNV		Internal $2,316.00 Sample External $3,126.60 Sample
10X Single Cell GEX		Internal $1,923.00 Sample External $2,596.05 Sample
3'-mRNA Library (QuantSeq)		Internal $99.00 Sample External $133.65 Sample
Aliquot/Transfer DNA		Internal $10.00 Sample External $13.50 Sample
Bead clean up		Internal $25.00 Sample External $33.75 Sample
Custom Capture - client kit		Internal $87.00 each External $117.45 each
DNA Library		Internal $104.00 Sample External $140.40 Sample
DNA Library (96 samples)		Internal $57.00 Sample External $76.95 Sample
DNA Library - client kit		Internal $78.00 Sample External $105.30 Sample
DNA QC		Internal $15.00 Sample External $20.25 Sample
Direct Lysis RNA Library		Internal $110.00 Sample External $148.50 Sample
Genomic DNA QC		Internal $17.00 Sample External $22.95 Sample
GridION Sequencing		Internal $2,041.00 each External $2,755.35 each
IDT Exome Capture		Internal $266.00 each External $359.10 each
Illumina Bead Array (w/o chip)		Internal $1,132.00 plate External $1,528.20 plate
Library QC		Internal $36.00 Sample External $48.60 Sample
MiSeq (Micro) 300 cycle,		Internal $813.00 each External $1,097.55 each
MiSeq (Nano) 300 cycle		Internal $666.00 each External $899.10 each
MiSeq (Nano) 500 cycle		Internal $723.00 each External $976.05 each
MiSeq (V2) 300 cycle		Internal $1,598.00 each External $2,157.30 each
MiSeq (V2) 50 cycle		Internal $1,344.00 each External $1,814.40 each
MiSeq (V2) 500 cycle		Internal $1,724.00 each External $2,327.40 each
MiSeq (V3) 150 cycle		Internal $1,457.00 each External $1,966.95 each
MiSeq (V3) 600 cycle		Internal $2,081.00 each External $2,809.35 each
NextSeq (HO) 150 cycle		Internal $3,471.00 each External $4,685.85 each
NextSeq (HO) 300 cycle		Internal $5,173.00 each External $6,983.55 each
NextSeq (HO) 75 cycle		Internal $2,117.00 each External $2,857.95 each
NextSeq (MO) 150 cycle		Internal $1,717.00 each External $2,317.95 each
NextSeq (MO) 300 cycle		Internal $2,375.00 each External $3,206.25 each
NovaSeq (S1) 100 cycle		Internal $6,292.00 each External $8,494.20 each
NovaSeq (S1) 200 cycle		Internal $7,405.00 each External $9,996.75 each
NovaSeq (S1) 300 cycle		Internal $7,850.00 each External $10,597.50 each
NovaSeq (S2) 100 cycle		Internal $10,471.00 each External $14,135.85 each
NovaSeq (S2) 200 cycle		Internal $12,418.00 each External $16,764.30 each
NovaSeq (S2) 300 cycle		Internal $13,086.00 each External $17,666.10 each
NovaSeq (S4) 200 cycle		Internal $18,476.00 each External $24,942.60 each
NovaSeq (S4) 300 cycle		Internal $20,408.00 each External $27,550.80 each
NovaSeq (SP) 100 cycle		Internal $3,972.00 each External $5,362.20 each
NovaSeq (SP) 300 cycle		Internal $4,973.00 each External $6,713.55 each
NovaSeq (SP) 500 cycle		Internal $6,309.00 each External $8,517.15 each
ONT Library Prep		Internal $202.00 Sample External $272.70 Sample
OpenArray Panel - client kit		Internal $369.00 plate External $498.15 plate
Pippin Size Selection		Internal $83.00 Sample External $112.05 Sample
RNA Library, client kit		Internal $125.00 Sample External $168.75 Sample
RNA QC		Internal $18.00 Sample External $24.30 Sample
Sequencing - client kit		Internal $1,560.00 each External $2,106.00 each
Small RNA Library		Internal $155.00 Sample External $209.25 Sample
Stranded mRNA Library		Internal $160.00 Sample External $216.00 Sample
Targeted Seq - client kit		Internal $607.00 plate External $819.45 plate
Total RNA Library		Internal $196.00 Sample External $264.60 Sample
TotalSeq Library Prep		Internal $162.00 Sample External $218.70 Sample
Visium GEX		Internal $5,347.00 slide External $7,218.45 slide
Visium GEX - client kit		Internal $527.00 slide External $711.45 slide
Visium Optimization		Internal $1,056.00 slide External $1,425.60 slide
Visium Optimization - client kit		Internal $268.00 slide External $361.80 slide
qPCR Instrument Usage		Internal $21.00 plate External $28.35 plate

Search available services: View: by category alphabetically

Name	Description	Price
▼ ► Quality Control Services (4)
DNA QC		Internal $15.00 Sample External $20.25 Sample
Genomic DNA QC		Internal $17.00 Sample External $22.95 Sample
Library QC		Internal $36.00 Sample External $48.60 Sample
RNA QC		Internal $18.00 Sample External $24.30 Sample
▼ ► NGS Library Prep Services (13)
Name	Description	Price
Custom Capture - client kit		Internal $87.00 each External $117.45 each
Direct Lysis RNA Library		Internal $110.00 Sample External $148.50 Sample
DNA Library		Internal $104.00 Sample External $140.40 Sample
DNA Library - client kit		Internal $78.00 Sample External $105.30 Sample
DNA Library (96 samples)		Internal $57.00 Sample External $76.95 Sample
IDT Exome Capture		Internal $266.00 each External $359.10 each
ONT Library Prep		Internal $202.00 Sample External $272.70 Sample
3'-mRNA Library (QuantSeq)		Internal $99.00 Sample External $133.65 Sample
RNA Library, client kit		Internal $125.00 Sample External $168.75 Sample
Small RNA Library		Internal $155.00 Sample External $209.25 Sample
Stranded mRNA Library		Internal $160.00 Sample External $216.00 Sample
Targeted Seq - client kit		Internal $607.00 plate External $819.45 plate
Total RNA Library		Internal $196.00 Sample External $264.60 Sample
▼ ► Single Cell Services (5)
Name	Description	Price
10X SC Immune Profiling		Internal $2,120.00 Sample External $2,862.00 Sample
10X Single Cell ATAC		Internal $1,732.00 Sample External $2,338.20 Sample
10X Single Cell CNV		Internal $2,316.00 Sample External $3,126.60 Sample
10X Single Cell GEX		Internal $1,923.00 Sample External $2,596.05 Sample
TotalSeq Library Prep		Internal $162.00 Sample External $218.70 Sample
▼ ► Next Generation Sequencing Services (26)
Name	Description	Price
GridION Sequencing		Internal $2,041.00 each External $2,755.35 each
MiSeq (Micro) 300 cycle,		Internal $813.00 each External $1,097.55 each
MiSeq (Nano) 300 cycle		Internal $666.00 each External $899.10 each
MiSeq (Nano) 500 cycle		Internal $723.00 each External $976.05 each
MiSeq (V2) 300 cycle		Internal $1,598.00 each External $2,157.30 each
MiSeq (V2) 50 cycle		Internal $1,344.00 each External $1,814.40 each
MiSeq (V2) 500 cycle		Internal $1,724.00 each External $2,327.40 each
MiSeq (V3) 150 cycle		Internal $1,457.00 each External $1,966.95 each
MiSeq (V3) 600 cycle		Internal $2,081.00 each External $2,809.35 each
NextSeq (HO) 150 cycle		Internal $3,471.00 each External $4,685.85 each
NextSeq (HO) 300 cycle		Internal $5,173.00 each External $6,983.55 each
NextSeq (HO) 75 cycle		Internal $2,117.00 each External $2,857.95 each
NextSeq (MO) 150 cycle		Internal $1,717.00 each External $2,317.95 each
NextSeq (MO) 300 cycle		Internal $2,375.00 each External $3,206.25 each
NovaSeq (S1) 100 cycle		Internal $6,292.00 each External $8,494.20 each
NovaSeq (S1) 200 cycle		Internal $7,405.00 each External $9,996.75 each
NovaSeq (S1) 300 cycle		Internal $7,850.00 each External $10,597.50 each
NovaSeq (S2) 100 cycle		Internal $10,471.00 each External $14,135.85 each
NovaSeq (S2) 200 cycle		Internal $12,418.00 each External $16,764.30 each
NovaSeq (S2) 300 cycle		Internal $13,086.00 each External $17,666.10 each
NovaSeq (S4) 200 cycle		Internal $18,476.00 each External $24,942.60 each
NovaSeq (S4) 300 cycle		Internal $20,408.00 each External $27,550.80 each
NovaSeq (SP) 100 cycle		Internal $3,972.00 each External $5,362.20 each
NovaSeq (SP) 300 cycle		Internal $4,973.00 each External $6,713.55 each
NovaSeq (SP) 500 cycle		Internal $6,309.00 each External $8,517.15 each
Sequencing - client kit		Internal $1,560.00 each External $2,106.00 each
▼ ► Spatial Transcriptomics Services (4)
Name	Description	Price
Visium GEX		Internal $5,347.00 slide External $7,218.45 slide
Visium GEX - client kit		Internal $527.00 slide External $711.45 slide
Visium Optimization		Internal $1,056.00 slide External $1,425.60 slide
Visium Optimization - client kit		Internal $268.00 slide External $361.80 slide
▼ ► Array Services (2)
Name	Description	Price
Illumina Bead Array (w/o chip)		Internal $1,132.00 plate External $1,528.20 plate
OpenArray Panel - client kit		Internal $369.00 plate External $498.15 plate
▼ ► Other Services (5)
Name	Description	Price
10X Data Processing - client prepped		Internal $127.00 each External $171.45 each
Bead clean up		Internal $25.00 Sample External $33.75 Sample
Aliquot/Transfer DNA		Internal $10.00 Sample External $13.50 Sample
Pippin Size Selection		Internal $83.00 Sample External $112.05 Sample
qPCR Instrument Usage		Internal $21.00 plate External $28.35 plate